Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the treatment method of a number of myeloma. Its synthesis or examine is vital for ensuring the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound within the synthesis of imatinib, a drug that targets unique different types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their study is crucial for optimizing the creation system and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to take care of breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist used in the treatment method of breast most cancers. Many intermediates CAS NO. 134790-39-9 help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and small cell lung cancer.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, CAS NO.949023-16-9 which have numerous applications, which include antiviral properties.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for type 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar amounts.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, that are Utilized in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor within the synthesis of canagliflozin, a medication utilised to control variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).